¹Division of Cardiology, University of Kinshasa Hospital, Kinshasa School of Medicine, University of Kinshasa, Kinshasa, The Democratic Republic of the Congo
²University KasaVubu School of Medicine, Boma, DR Congo
³Lomo-Medical Center, Kinshasa, DRCongo
⁴Higher Institute of Medical Technology (ISTM), Tshela
⁵BomaHospital, DR Congo
⁶Cité des Aveugles » Medical Center, Kinshasa, DRCongo

Background and Aim: The identification and management of cardiovascular risk factors become a major problem in people living with HIV before but especially after taking ARVs, hence the need to list these factors before in order to establish the proportion due to treatment
Methods: From January 1 to May 31, 2019; we conducted a cross-sectional and descriptive study at the Boma reference hospital located in the southeast and 440 Km from Kinshasa, the capital of DR Congo. Included was any patient infected with HIV aver 18 years and informed consent. Information on demographic parameters, behavioral lifestyles, anthropometric and biological (blood sugar, creatinine, urine strip and lipid profile) and blood pressure (BP) measurements was obtained.
Results: The most frequently reported cardiovascular risk factors: Age ≥ 55 Years 43.3%, Smoking 45%, Alcohol intake, 46.7%, HTN 15% and DM 13.3% significant between the two sexes
Conclusion: Les patients infectés par le VIH sont porteurs des plusieurs facteurs de risques cardiovasculaires

HIV infection, risk factors, Boma

1) Kharsany ABM and Karim QA. “HIV infection and AIDS in Sub-Saharan Africa: current status, challenges and opportunities”. Open AIDS Journal 10 (2016): 34-48.

2) Dwyer-Lindgren L., et al. “Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017”. Nature 570.7760 (2019): 189-193.

3) Escovitz GH. “The health transition in developing countries: a role for internists from the developed world”. Annals of InternalMedicine 116.6 (1992): 499-504.

4) World Organization. HIV/AIDS fact sheet 2016

5) Kibirige D and Sekitoleko R. Endocrine and metabolic abnormalities among HIV-infected patients:a current .Int J STD AIDS.2013;24(8):603-11

6) Feinstein M, Bahiru E, Achenbach C et al .Patterns of cardiovascular Mortality for HIV-infected Adult in the United Stated :1999-2013.Am.J.Cardiol 2016;117-1122.

7) Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006; 3: e442.

8) Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380(9859): 2224-60.

9) World Health Organization. Global Atlas on Cardiovascular Disease Prevention and Control. Mendis S, Puska P, Norrving B editors, WHO, Geneva, Switzerland.WHO library Cataloguing-in-Publication Data, 2011.

10) Paik IJ, Kotler DP. The prevalence and pathogenesis of diabetes mellitus in treated HIV infection. Best Pract Res ClinEndocrinolMetab. 2011;25: 469–78.

11) Bygbjerg IC. Double burden of noncommunicable and infectious diseases in developing countries. Science. 2012;337 (6101):1499–501.

12) Longo-Mbenza Benjamin MandinaNdonaMadone, Renzaho Andre, LepiraMbompaka François, Wumba -di-Mosi Roger et al. “Hypovitaminosis D, Aging, HIV Infection, HAART, and Other Cardiovascular Risk Factors in Patients from Kinshasa, Dr Congo, Central Africa”. EC Cardiology 6.10 (2019): 985-997.

13) Venables E., et al. “Even if she’s really sick at home, she will pretend that everything is fine: Delays in seeking care and treatment for advanced HIV disease in Kinshasa, demographic Republic of Congo”. PloS One 14.2 (2019): e0211619.

14) Vogt F., et al. “Brief report: decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC”. Journal of Acquired Immune Deficiency Syndromes 74.3 (2017): 326-331.

15) Katchunga B, Kabinda M , Matabaro M, Kashongwe M, Manyebwa J, M’Buyamba-Kabangu JR. Séroprévalence du Virus de l’Immunodéficience Humaine parmi les admissions cardiovasculaires à l’Hôpital Provincial Général de Référence de Bukavu, RD Congo. Sidanet, 2009, 6(9) : 1211

16) Williams B, Mancia G, Spiering W, et al. Guidelines for the management of arterial hypertension. EuropeanHeart Journal 2018; 39 (33):3021-104.

17) Report of the Expert Committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003; 26(Suppl 1): S5–20.13

18) World Health Organization (WHO). The problem of overweight and obesity: preventing and managing the global epidemic. Report Series 894; Geneva, WHO, 2000: 537

19) Orth SR, Stockmann A, Conradt C, Ritz E, Ferro M, Kreusser W and al. Smoking as a risk factor for end-stage renal failure in men with primary renal disease. Kidney Int. 2008; 54: 926-31.

20) Word Health OrganisationTWSatndrfsIW, Available at: http://www.who. int/ncds/surveillance/steps/STEPS_Manual 2017

21) Friedewald WT, Levi RI, Fredrickson DS. Estimation of the concentration of LDL-cholesterol without use of the preparative ultracentrifuge. ClinChem 1972; 18: 499–508.

22) Duval X, Gabriel B, Daniel G, Villes V, Dupré T, Leport C et al. Living with HIV, antiretroviral treatment experience and tobacco smoking: results from a multisite cross-sectional study. AntivirTher. 2008;13(3):389-397. PubMed | Google Scholar.

23) Coulibaly JC. Les affections neuro-méningées au cours de l'infection à VIH à la clinique des maladies infectieuses du CHNU de Fann: prévalence et facteurs associés au décès. Thèse Med Dakar. 201 n°29.

24) Dandona L, Dandona R, Kumar GA, et al. Risk factors associated with HIV in a population-based study in Andhra Pradesh state of India. Int J Epidemiol 2008;37:1274-86 [PubMed] [Google Scholar]

25) Perkins JM, Khan KT, Subramanian SV. Patterns and distribution of HIV among adult men and women in India. PLoS ONE 2009;4:e5648

26) Blaise MakosoNimi, François LepiraBompeka, Aliocha Nkodila, Williams Ilenga,Gédeon Long-Longo, Dieudonné VanguNgoma,et al . Prehypertension, Hypertension and Associated Risk Factors among Adults Living in the Port City of Boma in the Democratic Republic of the Congo. A Population-Based Cross-Sectional Survey”. Acta Scientific Cancer Biology 4.5 (2020): 24-32.

27) FelistasMashinya , Marianne Alberts , Jean.Pierre Van geertruyden and Robert Colebunders. Assessment of cardiovascular risk factors in people with HIV infection treated with ART in rural South Africa: a cross sectional study. AIDS Res Ther (2015) 12:42

28) Obesité, hypertension artérielle,hypercholesterolemia et diabete sucré non traits chez les adultes infectés ou pas par le VIH à Mbuji-Maji.Bull.Soc.Pathol.Exo.2017 ;110 :300-309.

29) Kwarisiima D, Balzer L, Heller D, KotwaniP,Chamie G, Tamara C,et al. Population-based assessment of hypertension epidemiology and risk factors among HIV-positive and general populations in rural Uganda. PLoS One 2016;11 :e0156309.

30) Mayne ES, George JA. Mortal allies: human immunodeficiency virus and noncommunicable diseases. CurrOpin HIV AIDS 2017;12:148–56

31) Kwarisiima D, Balzer L, Heller D, et al. Population-based assessment of hypertension epidemiology and risk factors among HIV-positive and general populations in rural Uganda. PLoS One 2016;11:e0156309.

32) Vos A, Devillé W, Barth R, et al. HIV infection and cardiovascular risk profile in a rural South African population: the Ndlovu Cohort Study. BMJ Global Health 2017;2(Suppl 2):A10.1–A10.

33) Dillon DG, Gurdasani D, Riha J, et al. Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: a systematic review and meta-analysis. Int J Epidemiol 2013 ;42:1754–71.

34) Blaise MakosoNimi, François LepiraBompeka,Benjamin Longo Mbenza, Roland VanguVangu et al .Prevalence of Undiagnosed Hypertension among the Hypertensives Living in the City of Boma. Democratic Republic of the Congo. IJISRT , 2020;5(6):197-204.

35) Alebiosu OC, Familoni OB, Ogunsemi OO, et al. Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321). Indian J EndocrinolMetab 2013;17:653.

36) Isa SE, Oche AO, Kang'ombe AR, et al. Human Immunodeficiency Virus and Risk of Type 2 Diabetes in a Large Adult Cohort in Jos, Nigeria.

37) Blaise MakosoNimi, François LepiraBompeka, Gedeon Longo Longo, Benjamin Longo Mbenza, AliochaNkodila and ElyséeBuangaKhuabi.Hypertension and Associated Cardiovascular Risk Factors among Adult in Boma City. Democratic Republic of the Congo.IJMSCR.2020;3(4):682-692.

38) Gerald SB, Joseph WH, Alfred K, et al. Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in western Kenya. Plos One 2011; 6(7): 14.

39) Edward AO, Oladayo AA, Omolola AS, Adetiloye AA, Adedayo PA. Prevalence of traditional cardiovascular risk factors and evaluation of cardiovascular risk using three risk equations in Nigerians living with human immunodeficiency virus. N Am J Med Sci. 2013;5(12):680–8.

40) Abebe M, Kinde S, Belay G, Gebreegziabxier A, Challa F, Gebeyehu T, et al. Antiretroviral treatment associated hyperglycemia and dyslipidaemia among HIV infected patients at Burayu Health Center, Addis Ababa, Ethiopia: a cross-sectional comparative study. BMC Res Notes. 2014;7:380–7.

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